Dihydro nicotinamide mononucleotide (NMNH) is the reduced-form of nicotinamide mononucleotide (NMN), which was naturally occurred in kidney, act as a better NAD+ enhancer compared to NMN. NMNH could convert to NAD+ rapidly in vivo, which is two times higher than NMN in speed and concentration，and also increase the NAD+ level in a variety of tissues. NMNH could reduce cell damage under hypoxia condition by enhancing repair. In addition, Additionally, NMNH increased the NADH level in cells and in mouse liver, suppresses glycolysis and TCA cycle.
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