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Industry News

15 Mar 2024

Targeting NAD+ Salvage Pathway as a Potential Approach to Combat Obesity

Introduction Mar 4th is determined as the World Obesity Day. World Obesity Federation, UNICEF and WHO have hosted a global youth-led webinar to talk about obesity & youth. The obesity crisis has gradually attr

13 Mar 2024

Tailoring Personalized Dosage Regimens of NMN Based on NAD Concentration

Introduction Nicotinamide mononucleotide (NMN), one precursor of nicotinamide adenine dinucleotide (NAD+), has been ascertained to be implicated with multiple biological processes such as cellular redox regulation and

12 Mar 2024

NR as a Promising Therapeutic Candidate for Alpers' Disease

Introduction Alpers' disease is both a neurodegenerative disorder and a metabolic disorder, which is tightly linked to mitochondrial dysfunction and mutations in the catalytic subunit of polymerase

11 Mar 2024

Deep Insight on NADH: a Potential Medical Arsenal

Introduction NADH (reduced form of NAD+) serves as a carrier of biological hydrogen and an electron donor, which participates in diverse physiological processes such as protein synthesis, DNA repair,

07 Mar 2024

Frontier Dynamics on the Molecular Mechanism of Ginsenoside Rh2 Against Tumor

Introduction Ginsenoside Rh2, one protopanaxadiol (PPD)-type rare ginsenoside in Panax ginseng, is uncovered to possibly have broad-spectrum pharmacological activity in diversified tumors. It is utili

05 Mar 2024

SLC25A51 Functions as an NAD+/NADH Redox Decoupler in AML

Introduction Solute carrier family 25 member 51 (SLC25A51) is perceived as a mammalian transporter, which is capable of importing oxidized nicotinamide adenine dinucleotide (NAD+) into mitochondrial matrix. Remark

04 Mar 2024

The Molecular Mechanisms Underlying the Interaction Between NAD+/NMN and DBC1

Introduction Oxidized form of nicotinamide adenine dinucleotide (NAD+) and its precursor nicotinamide mononucleotide (NMN) have been uncovered to restore DNA repair and prevent cancer progression via the deleted i

29 Feb 2024

Protective Role of NAD+ Against MI-induced HF in Sprague-Dawley Rats and Beagles

1. Introduction Disrupted nicotinamide adenine dinucleotide (NAD+) metabolism is increasingly deemed to be one of risk factor for amendable cardiovascular disorders. A substantial evidence has mirrored that res

28 Feb 2024

Investigating the Great Possibility of Rare Ginsenosides as Drugs and Nutraceuticals

1. Introduction Rare ginsenosides, a group of dammarane triterpenoids that exist in low natural abundance, fuels a high concern from scholars recently, showing great potential as shining components in drugs and nu