Advantages of NMNH
NMNH: 1. “Bonzyme” Whole-enzymatic method, environmental-friendly, no harmful solvent residues manufacturing powder. 2. Bontac is a very first manufacture in the world to produce the NMNH powder on the level of high purity, stability. 3. Exclusive “Bonpure” seven-step purification technology, high purity（up to 99%) and stability of production of NMNH powder 4. Self-owned factories and obtained a number of international certifications to ensure high quality and stable supply of products of NMNH powder 5. Provide one-stop product solution customization service
Advantages of NADH
NADH: 1. Bonzyme whole-enzymatic method, environmental-friendly, no harmful solvent residues 2. Exclusive Bonpure seven-step purification technology, purity up higher than 98 % 3. Special patented process crystal form, higher stability 4. Obtained a number of international certifications to ensure high quality 5. 8 domestic and foreign NADH patents, leading the industry 6. Provide one-stop product solution customization service
Advantages of NAD
NAD: 1. “Bonzyme” Whole-enzymatic method, environmental-friendly, no harmful solvent residues 2. Stable supplier of 1000+ enterprises around the world 3. Unique “Bonpure” seven-step purification technology, higher product content and higher conversion rate 4. Freeze drying technology to ensure stable product quality 5. Unique crystal technology, higher product solubility 6. Self-owned factories and obtained a number of international certifications to ensure high quality and stable supply of products
Advantages of MNM
NMN: 1. “Bonzyme”Whole-enzymatic method, environmental-friendly, no harmful solvent residues 2. Exclusive“Bonpure”seven-step purification technology, high purity（up to 99.9%) and stability 3. Industrial leading technology: 15 domestic and international NMN patents 4. Self-owned factories and obtained a number of international certifications to ensure high quality and stable supply of products 5. Multiple in vivo studies show that Bontac NMN is safe and effective 6. Provide one-stop product solution customization service 7. NMN raw material supplier of famous David Sinclair team of Harvard University
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Bontac Bio-Engineering (Shenzhen) Co., Ltd. (hereafter referred to as BONTAC) is a high-tech enterprise established in July 2012. BONTAC integrates R&D, production and sales, with enzyme catalysis technology as the core and coenzyme and natural products as main products. There are six major series of products in BONTAC, involving coenzymes, natural products, sugar substitutes, cosmetics, dietary supplements and medical intermediates.
As the leader of the global NMN industry, BONTAC has the first whole-enzyme catalysis technology in China. Our coenzyme products are widely used in health industry, medical & beauty, green agriculture, biomedicine and other fields. BONTAC adheres to independent innovation, with more than 170 invention patents. Different from the traditional chemical synthesis and fermentation industry, BONTAC has advantages of green low-carbon and high-value-added biosynthesis technology. What’s more, BONTAC has established the first coenzyme engineering technology research center at the provincial level in China which also is the sole in Guangdong Province.
In the future, BONTAC will focus on its advantages of green, low-carbon and high-value-added biosynthesis technology, and build ecological relationship with academia as well as upstream/downstream partners, continuously leading the synthetic biological industry and creating a better life for human beings.
NADH powder manufacturing method
The main methods of NADH powder preparation include extraction, fermentation, fortification, biosynthesis and organic matter synthesis. Compared with other preparations, the whole enzyme become the mainstream method owing to the advantages of pollution free, high level of purity and stability.
BONTAC NADH product features and advantages
1、“Bonzyme”Whole-enzymatic method, environmental-friendly, no harmful solvent residues manufacturing powder
2、Exclusive“Bonpure” seven-step purification technology, high purity（up to 99%) and stability of production of NADH powder
3、Self-owned factories and obtained a number of international certifications to ensure high quality and stable supply of products of NMN powder
4、Provide one-stop product solution customization service
NADH powder efficacy in health
Improved energy levels
Not only does NADH act as an important coenzyme in aerobic respiration, the [H] of NADH also carries a large amount of energy. Studies have demonstrated that extracellular use of NADH promotes increased intracellular ATP levels, suggesting that NADH penetrates cell membranes and elevates intracellular energy levels. On a macro level, exogenous supplementation of NADH helps to restore energy and enhance appetite. The increase in energy levels in the brain also helps to improve mental performance and sleep quality. NADH has been used overseas to improve chronic fatigue syndrome, increase exercise endurance, jet lag and other areas.
Cellular protection
NADH is a strong antioxidant that naturally occurs in cells and reacts with free radicals to inhibit lipid peroxidation, protecting mitochondrial membranes and mitochondrial function. It has been found that NADH can reduce oxidative stress in cells caused by various factors such as radiation, drugs, toxic substances, strenuous exercise and ischemia, thus protecting vascular endothelial cells, hepatocytes, cardiomyocytes, fibroblasts and neurons. Therefore, injectable or oral NADH is used clinically to improve cardiovascular and cerebrovascular diseases, and as an adjunct to cancer radiotherapy. Topical NADH has been shown to be effective in the treatment of rosacea and contact dermatitis.
Promotion of neurotransmitter production
Studies have shown that NADH significantly promotes the production of the neurotransmitter dopamine, a chemical signal that is essential for short-term memory, involuntary movements, muscle tone and spontaneous physical responses. It also mediates the release of growth hormone and determines muscle movement. Without sufficient dopamine, muscles become stiff. Parkinson's disease, for example, is caused in part by a disruption of dopamine synthesis in brain cells. Preliminary clinical data suggest that NADH can help improve the symptoms of Parkinson's disease [9]. NADH also promotes the biosynthesis of norepinephrine and serotonin, showing good potential for use in the relief of depression and Alzheimer's disease.
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Frequently Asked Question
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NADH is synthesized by the body and thus is not an essential nutrient. It does require the essential nutrient nicotinamide for its synthesis, and its role in energy production is certainly an essential one. In addition to its role in the mitochondrial electron transport chain, NADH is produced in the cytosol. The mitochondrial membrane is impermeable to NADH, and this permeability barrier effectively separates the cytoplasmic from the mitochondrial NADH pools. However, cytoplasmic NADH can be used for biologic energy production. This occurs when the malate-aspartate shuttle introduces reducing equivalents from NADH in the cytosol to the electron transport chain of the mitochondria. This shuttle mainly occurs in the liver and heart.
The action of supplemental NADH is unclear. Oral NADH supplementation has been used to combat simple fatigue as well as such mysterious and energy-sapping disorders as chronic fatigue syndrome and fibromyalgia. Researchers are also studying the value of NADH supplements for improving mental function in people with Alzheimer's disease, and minimizing physical disability and relieving depression in people with Parkinson's disease. Some healthy individuals also take NADH supplements orally to improve concentration and memory capacity, as well as to increase athletic endurance. However, to date there have been no published studies to indicate that using NADH is in any way effective or safe for these purposes
First, inspect the factory. After some screening, NADH companies that directly face consumers pay more attention to brand building. Therefore, for a good brand, quality is the most important thing, and the first thing to control the quality of raw materials is to inspect the factory. Bontac company actually manufacturing NADH powder of high quality with the caterias of SGS. Secondly, the purity is tested. Purity is one of the most important parameters of NMN powder. If high purity NMN cannot be guaranteed, the remaining substances are likely to exceed the relevant standards. As the attached certificates demonstrates that the NADH powder produced by Bontac reach the purity of 99%. Finally, a professional test spectrum is needed to prove it. Common methods for determining the structure of an organic compound include Nuclear Magnetic Resonance Spectroscopy (NMR) and high-resolution mass spectrometry (HRMS). Usually through the analysis of these two spectra, the structure of the compound can be preliminarily determined.
Our updates and blog posts
BONTAC is looking forward to your arrival at Booth No. 3A53 in 2024 PCHi
On March 20~22, 2024, Personal Care & Home Ingredients Shanghai (PCHi) will be held in Shanghai World Expo Exhibition & Convention Center. BONTAC’s active raw materials for high-end cosmetics will be displayed at Booth No. 3A53 in 2024 PCHi, including but not limited to NMN, Pro-Xylane, Rare Ginsenoside Rh2/Rg3, Ergothioneine, Salidroside and Type III Recombinant Collagen. BONTAC has been dedicated to provide high-quality raw materials of coenzymes and natural products for 12 years. Looking forward to seeing you at site. BONTAC Product List Niche Area Products Application Scope NMN (CAS No.: 1094-61-7) Healthcare products; Cosmetics; Medicine NAD (CAS No.: 53-84-9) Healthcare products; Cosmetics; Diagnostic reagents Raw materials for enzyme catalysis; Animal health Coenzyme Endotoxin-free grade NADH (CAS No.: 606-68-98) Functional food and drink; Biomedical research and development Healthcare product; Diagnostic reagents NADP (CAS No.: 24292-60-2/1184-16-3) Raw materials for medicine or enzyme catalysis; Diagnostic reagents; In vitro diagnostic reagents (GR); Biomedical research and development S-NAD (CAS No.: 4090-29-3) Biochemical diagnostic reagents NR (CAS No.: 23111-00-4) Healthcare products; Cosmetics; Diagnostic reagent Natural products Ginsenoside Rh2(CAS No.：78214-33-2) Healthcare products; Cosmetics; Drink; Alcohol; Medicine; Functional food Ginsenoside Rg3(Cas No. : 38243-03-7) Salidroside (Cas No.: 10338-51-9) Healthcare products; Scientific research experiment; New drug development Stevia Sweetener (RD)(Cas No.: 63279-13-0 ) Food; Drink; Daily chemical industry; Brewing Raw materials for cosmetics Pro-Xylane (CAS No.: 439685-79-7) Cosmetics Erythrothioneine Cosmetics Dietary supplements L-Glutathione Reduced Healthcare products; Cosmetics Resveratrol Healthcare products; Cosmetics Phosphatidylserine Healthcare products; Biochemical diagnostic reagent Medicine and intermediate Ursodeoxycholic acid(CAS No.: 128-13-2) Healthcare products; Biochemical diagnostic reagent Chenodeoxycholic acid Healthcare products; Biochemical diagnostic reagent Cholic acid Healthcare products; Biochemical diagnostic reagents BONTAC profile Bontac Bio-Engineering (Shenzhen) Co., Ltd. (also referred to as BONTAC) is a high-tech enterprise established in July 2012. BONTAC integrates R&D, production and sales. There are six major series of product in BONTAC, involving coenzymes, natural products, sugar substitutes, cosmetics, dietary supplements and medical intermediates. BONTAC is the pioneer of NMN industry. By virtue of the first whole-enzyme catalysis technology in China, BONTAC takes the industry lead in its niche field of coenzyme. Our coenzyme products are widely used in health industry, medical & beauty, green agriculture, biomedicine and other fields. BONTAC adheres to independent innovation, with more than 170 invention patents. Different from the traditional chemical synthesis and fermentation industry, BONTAC has advantages of green low-carbon and high-value-added biosynthesis technology. BONTAC has undertaken a number of provincial and national science projects in China, with the only approved "coenzyme engineering technology research center" in Guangdong China. In the future, BONTAC will continue to build ecological relationship with academia, and upstream/downstream partners, lead the synthetic biological industry and create a better life for human beings.
BONTAC Shines at Health Food Ingredients/OEM Expo
Introduction On April 24th 2024, BONTAC was invited to participant in the 26th Health Food Ingredients/OEM Expo (ie. Health Food Expo, Ingredients and Contract Manufacture) in Tokyo International Exhibition Hall E1, Japan. This exhibition achieved full success. About Health Food Ingredients OEM exhibition Health Food Ingredients/OEM Expo is one the of Japan's only exhibition specializing in BtoB in the realm of health food ingredients and OEM, which is held in world-famous Tokyo International Forum. The name of this exhibition was switched from “International Health Ingredient Seminar & Expo” in 1998 to “Functional Food Expo” in 2002, and then changed to “Health Food Expo, Ingredients and Contract Manufacture” for further specialization of this event. Notably, there are more than 10,000 visitors attending the Health Food Ingredients/OEM Expo in Japan this year. Keynote speech by the BONTAC founder As a special guest, Dr. Cheung, the chief scientist and founder in BONTAC, delivered a keynote speech titled “Independent Wholechain Technology for Coenzyme Synthesis” in this exhibition, wining the high praise from the audiences on the spot. Dr. Cheung shared how BONTAC broke through the bottleneck of coenzyme synthesis technology to realize the independent control of the whole chain from raw material screening, enzyme engineering modification to industrialized production. The coenzyme synthesis technology independently innovated by BONTAC not only greatly improves the purity and stability of coenzyme products, but also effectively reduces the production cost. Dr. Cheung highlighted the important role of scientific research and innovation in promoting industrial progress. BONTAC Vision In the future, BONTAC will continue to be committed to scientific and technological innovation, through the independent control of the whole chain, to provide consumers with higher quality and more cost-effective health food raw materials, aiming to create a healthier and better life for human beings.
Powering Health and Vitality: BONTAC's Metabolism-boosting Product Portfolio
Powering Health and Vitality: BONTAC's Metabolism-boosting Product Portfolio In the dynamic landscape of health and wellness, the demand for cutting-edge metabolism-boosting products continues to soar. At BONTAC, we are proud to offer a diverse range of metabolism-boosting products meticulously designed to enhance cellular function, optimize metabolism-boosting health, and support overall well-being. The world of metabolism-boosting products has witnessed a remarkable evolution, and as trailblazers in the industry, BONTAC understands the significance of staying at the forefront of metabolism-boosting product development. Our dedicated team of experts tirelessly engages in research and innovation, ensuring that our metabolism-boosting products remain on the cutting edge of the industry. By constantly pushing boundaries and challenging conventional norms, we strive to deliver products that exceed expectations and address the ever-evolving needs of our valued customers. The Evolution of metabolism-boosting Products As pioneers in the industry, BONTAC recognizes the importance of staying ahead of the curve in metabolism-boosting product development. Our team of experts works tirelessly to research and innovate, ensuring that our metabolism-boosting products are at the forefront of the industry. Through a commitment to excellence and continuous improvement, we strive to meet the evolving needs of our customers. Through a steadfast commitment to excellence and a relentless pursuit of continuous improvement, we are able to anticipate emerging trends and embrace groundbreaking advancements in metabolism-boosting science. This enables us to develop innovative formulations that meet or even surpass the expectations of our discerning clientele. By harnessing the power of scientific knowledge and leveraging the latest technologies, we create metabolism-boosting products that are not only effective but also safe, reliable, and tailored to the unique requirements of individuals seeking to optimize their metabolism-boosting health. Benefits of BONTAC's metabolism-boosting Product Range BONTAC's metabolism-boosting product range is crafted with precision to enhance cellular function and energy metabolism. Our products are formulated to support optimal metabolism-boosting health, providing a foundation for long-term wellness. From boosting energy levels to optimizing metabolism-boosting processes, BONTAC's metabolism-boosting products are designed to empower individuals to live their best and healthiest life. Collaborating with BONTAC for metabolism-boosting Success When you partner with BONTAC, you gain access to customized solutions tailored to your unique business needs. Our team is dedicated to providing top-tier technical support and expertise in the metabolism-boosting industry, ensuring that you receive the guidance and resources necessary to achieve success. By partnering with BONTAC, you can leverage our commitment to technical innovation and tap into our extensive business coverage to reach new heights in the health and wellness market. Conclusion In conclusion, BONTAC's metabolism-boosting product portfolio represents the pinnacle of excellence, technical innovation, and unwavering commitment to customer success. Our products are characterized by their effectiveness, quality, and unique features that set them apart in the market. Join us on the journey to better health and vitality with BONTAC's exceptional metabolism-boosting products that are designed to transform life and empower individuals to thrive.