A brief introduction to nad manufacturer | BONTAC

A brief introduction to nad manufacturer | BONTAC

In general, there are three main manufacture methods for NAD preparation utilized by NAD manufacturers in the world such as chemical or enzymatic synthesis, and fermentation biosynthesis. And at present, the NAD manufacturers are located worldwide including China, America, Japan and German.
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Advantages of NMNH

NMNH: 1. “Bonzyme” Whole-enzymatic method, environmental-friendly, no harmful solvent residues manufacturing powder. 2. Bontac is a very first manufacture in the world to produce the NMNH powder on the level of high purity, stability. 3. Exclusive “Bonpure” seven-step purification technology, high purity(up to 99%) and stability of production of NMNH powder 4. Self-owned factories and obtained a number of international certifications to ensure high quality and stable supply of products of NMNH powder 5. Provide one-stop product solution customization service

Advantages of NADH

NADH: 1. Bonzyme whole-enzymatic method, environmental-friendly, no harmful solvent residues 2. Exclusive Bonpure seven-step purification technology, purity up higher than 98 % 3. Special patented process crystal form, higher stability 4. Obtained a number of international certifications to ensure high quality 5. 8 domestic and foreign NADH patents, leading the industry 6. Provide one-stop product solution customization service

Advantages of NAD

NAD:  1. “Bonzyme” Whole-enzymatic method, environmental-friendly, no harmful solvent residues 2. Stable supplier of 1000+ enterprises around the world 3. Unique “Bonpure” seven-step purification technology, higher product content and higher conversion rate 4. Freeze drying technology to ensure stable product quality 5. Unique crystal technology, higher product solubility 6. Self-owned factories and obtained a number of international certifications to ensure high quality and stable supply of products

Advantages of MNM

NMN:  1. “Bonzyme”Whole-enzymatic method, environmental-friendly, no harmful solvent residues 2. Exclusive“Bonpure”seven-step purification technology, high purity(up to 99.9%) and stability 3. Industrial leading technology: 15 domestic and international NMN patents 4. Self-owned factories and obtained a number of international certifications to ensure high quality and stable supply of products 5. Multiple in vivo studies show that Bontac NMN is safe and effective 6. Provide one-stop product solution customization service 7. NMN raw material supplier of famous David Sinclair team of Harvard University

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Bontac Bio-Engineering (Shenzhen) Co., Ltd. (hereafter referred to as BONTAC) is a high-tech enterprise established in July 2012. BONTAC integrates R&D, production and sales, with enzyme catalysis technology as the core and coenzyme and natural products as main products. There are six major series of products in BONTAC, involving coenzymes, natural products, sugar substitutes, cosmetics, dietary supplements and medical intermediates.

As the leader of the global NMN industry, BONTAC has the first whole-enzyme catalysis technology in China. Our coenzyme products are widely used in health industry, medical & beauty, green agriculture, biomedicine and other fields. BONTAC adheres to independent innovation, with more than 170 invention patents. Different from the traditional chemical synthesis and fermentation industry, BONTAC has advantages of green low-carbon and high-value-added biosynthesis technology. What’s more, BONTAC has established the first coenzyme engineering technology research center at the provincial level in China which also is the sole in Guangdong Province.

In the future, BONTAC will focus on its advantages of green, low-carbon and high-value-added biosynthesis technology, and build ecological relationship with academia as well as upstream/downstream partners, continuously leading the synthetic biological industry and creating a better life for human beings.

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NAD powder efficacy in health

Molecules that can be taken in supplement form to increase NAD levels in the body are referred to by some as “NAD boosters.” Studies conducted over the past six decades suggest that the following are some of the many benefits associated with taking an NAD supplement:
Can Help Restore Mitochondrial Function
Helps Repair Blood Vessels —A 2018 mice study found that supplementation could aid in repair and growth of aged blood vessels. There’s also some evidence it can help manage heart disease risk factors like high blood pressure and high cholesterol.
May Improve Muscle Function — One animal study conducted in 2016 found that degenerative muscles had improved muscle function when supplemented with NAD+ precursors.
Potentially Helps Repair Cells and Damaged DNA — Some studies have found evidence that NAD+ precursor supplementation leads to an increase in DNA damage repair. NAD+ is broken down into two component parts, nicotinamide and ADP-ribose, which combine with proteins to repair cells.
May Help Improve Cognitive Function — Several studies conducted on mice have found that mice treated with NAD+ precursors experienced improvements in cognitive function, learning and memory. Findings have led researchers to believe that NAD supplement may help protect against cognitive decline/Alzheimer’s disease.
May Help Prevent Age-Related Weight Gain — A 2012 study showed that when mice fed a high-fat diet were given an NAD supplement, they gained 60 percent less weight than they did on the same diets without the supplement. One reason this may be true is that nicotinamide adenine dinucleotide helps regulate production of stress- and appetite-related hormones, thanks to its effects on circadian rhythms.
Precursors are molecules used in chemical reactions inside the body to create other compounds. There are a number of precursors of NAD+ that result in higher levels when you consume enough of them.

NAD powder efficacy in health

NAD powder manufacturing method

The preparation methods utilized by manufacturers worldwide of NAD powder are mainly divided into chemical synthesis method and biocatalytic method, among which biocatalytic method includes biological fermentation method and enzyme catalysis method. Enzyme catalysis method has gradually become the mainstream direction because of its advantages of green, environmental protection and pollution-free. And then the purity of NAD powder will reach 99% after the procedure of further purifying. But some NAD manufacturers tend to choose the multiple methods to develop the producing of NAD.

NAD powder manufacturing method

BONTAC NAD product features and advantages

1、As an advanced technology NAD manufacturer,  BONTAC  choose the Enzymatic method, environmental-friendly, no harmful solvent residues manufacturing powder 
2、High purity(up to 99%) and stability of production of NAD powder 
3、Self-owned factories and obtained a number of international certifications to ensure high quality and stable supply of products of NAD powder  
4、Multiple in vivo studies show that Bontac NAD powder is safe and effective
5、Provide one-stop product solution customization service

BONTAC NAD product features and advantages
User Reviews

What users say about BONTAC

BONTAC is a reliable partner that we have been working with for many years. The purity of their coenzyme is very high. Their COA can achieve relatively high test results.

Front

I discovered BONTAC in 2014 because David's article in cell about NAD and NMN related showed that he used BONTAC's NMN for his experimental material. Then we found them in China. After so many years of cooperation, I think it is a very good company.

Hanks

I think green, healthy and high purity are the advantages of BONTAC's products compared with others. I still work with them to this day.

Phillip

In 2017, we chose BONTAC's coenzyme, during which our team encountered many technical problems and consulted their technical team, which were able to give us good solutions. Their products are shipped very fast and they work more efficiently.

Gobbs
Frequently Asked Question

Do you have any question?

1.Prevention and treatment of viral-induced inflammatory storms
Scientists have found after extensive research that neo-coronavirus has a mechanism similar to SARS virus to activate inflammatory vesicles NLRP3. and the activation of NLRP3 produces more inflammatory factors, generating excessive inflammation and thus triggering a deadly cytokine storm. This problem can be well addressed by NAD+, which inhibits the activity of NF-κB inflammatory pathway and NLRP3 inflammasome by increasing the activity of sirtuins (SIRT1, SIRT2 and SIRT3), thus preventing cytokine storm caused by excessive inflammation. Therefore, Sinclair and other scientists believe that increasing the concentration of NAD+ may play an important role in the prevention and treatment of neocoronavirus and other viral infections.
2.Restoration of virus-induced metabolic disorders
NAD+ is an essential coenzyme for many cellular energy metabolic pathways, present in every cell of the body, involved in thousands of reactions, and an important player in maintaining cellular viability. In the COVID-19 infection model, NAD+ and NMN supplementation was found to be effective in alleviating cell death and protecting the lung.

First, inspect the factory. After some screening, NAD manufactures that directly face consumers pay more attention to brand building. Therefore, for a good brand, quality is the most important thing, and the first thing to control the quality of raw materials is to inspect the factory. Bontac company actually manufacturing NAD powder of high quality with the caterias of SGS. Secondly, the purity is tested. Purity is one of the most important parameters of NAD powder. If high purity NAD cannot be guaranteed, the remaining substances are likely to exceed the relevant standards. As the attached certificates demonstrates that the NAD powder produced by Bontac reach the purity of 99.9%. Finally, a professional test spectrum is needed to prove it. Common methods for determining the structure of an organic compound include Nuclear Magnetic Resonance Spectroscopy (NMR) and high-resolution mass spectrometry (HRMS). Usually through the analysis of these two spectra, the structure of the compound can be preliminarily determined.

In the international market, NAD+ food supplements are in production in the United States, the Australian Food and Drug Administration has approved NAD+ products for sale, and Japanese NAD+ manufactures are devoted to extend the market share in China. Li Ka-shing invested HK$200 million in the US NAD manufacturer, whose NAD+ products are being sold by Watsons in Hong Kong! Then Mclane, a company owned by Warren Buffett also joined the NAD market.

Our updates and blog posts

BONTAC Shines at Health Food Ingredients/OEM Expo

Introduction On April 24th 2024, BONTAC was invited to participant in the 26th Health Food Ingredients/OEM Expo (ie. Health Food Expo, Ingredients and Contract Manufacture) in Tokyo International Exhibition Hall E1, Japan. This exhibition achieved full success. About Health Food Ingredients OEM exhibition Health Food Ingredients/OEM Expo is one the of Japan's only exhibition specializing in BtoB in the realm of health food ingredients and OEM, which is held in world-famous Tokyo International Forum. The name of this exhibition was switched from “International Health Ingredient Seminar & Expo” in 1998 to “Functional Food Expo” in 2002, and then changed to “Health Food Expo, Ingredients and Contract Manufacture” for further specialization of this event. Notably, there are more than 10,000 visitors attending the Health Food Ingredients/OEM Expo in Japan this year. Keynote speech by the BONTAC founder As a special guest, Dr. Cheung, the chief scientist and founder in BONTAC, delivered a keynote speech titled “Independent Wholechain Technology for Coenzyme Synthesis” in this exhibition, wining the high praise from the audiences on the spot. Dr. Cheung shared how BONTAC broke through the bottleneck of coenzyme synthesis technology to realize the independent control of the whole chain from raw material screening, enzyme engineering modification to industrialized production. The coenzyme synthesis technology independently innovated by BONTAC not only greatly improves the purity and stability of coenzyme products, but also effectively reduces the production cost. Dr. Cheung highlighted the important role of scientific research and innovation in promoting industrial progress. BONTAC Vision In the future, BONTAC will continue to be committed to scientific and technological innovation, through the independent control of the whole chain, to provide consumers with higher quality and more cost-effective health food raw materials, aiming to create a healthier and better life for human beings.

Nourishing Wellness: BONTAC as a Leading Raw Material Supplier of Supplements

Nourishing Wellness: BONTAC as a Leading Raw Material Supplier of Supplements As a prominent raw material supplier of supplements, BONTAC is dedicated to developing and delivering premium products that promote health and well-being through innovative formulations and exceptional quality. We are committed to developing and delivering premium raw materials that fuel the success of your health and wellness products. With our focus on technical innovation, comprehensive business coverage, and dedicated technical support, we stand out as a leading partner for your raw material needs. Expertise in Nutraceutical Formulations BONTAC boasts a team of experts who excel in the development of nutraceutical formulations. Our blend of scientific knowledge and creativity enables us to create effective and advanced formulations that meet the highest standards of quality and efficacy. Through rigorous research and stringent quality control measures, we ensure that our raw materials contribute to the optimal results and success of your supplements. Diverse Range of Nutraceutical Products   Deepening our understanding of cellular rejuvenation has been a core focus at BONTAC. We delve into various scientific disciplines, from molecular biology and genetics to epigenetics and regenerative medicine, to unravel the intricate processes that govern cellular aging and rejuvenation. Armed with this knowledge, we develop cutting-edge raw materials that promote cellular rejuvenation, allowing your products to tap into the body's natural ability to restore and regenerate itself. A Diverse Range of Nutraceutical Solutions   Exploring BONTAC's extensive range of nutraceutical raw materials reveals a diverse array of products tailored to address various health needs. From immune support and stress management to dietary supplements and performance enhancers, each raw material is carefully crafted to deliver specific benefits. Our innovative ingredients, unique formulations, and proven efficacy in supporting overall health and wellness set our nutraceutical offerings apart from the competition. Partnering with BONTAC for Nutraceutical Excellence By partnering with BONTAC, businesses in the supplements industry can access customized strategies and high-quality raw materials that align with their health and wellness initiatives. Our dedicated technical support team will guide you in selecting the right raw materials and seamlessly integrating them into your product offerings. With BONTAC as your trusted partner, you can leverage our expertise, technical innovations, and extensive business coverage to elevate your product lines and provide exceptional value to your customers. Conclusion In conclusion, BONTAC's position as a leading raw material supplier of nutraceuticals stems from our unwavering commitment to excellence, technical innovation, and exceptional raw materials. By choosing BONTAC as your preferred supplier, you gain access to our expertise, quality raw materials, and dedication to helping your nutraceutical business thrive. Partner with us today and unlock the full potential of your health and wellness products.

What is Pure NMN Powder? Its Potential Benefits and 4 Basic Applications

Aging is an undeniable reality of life. It is a known fact that with increasing age, different body functions tend to decline. While we may not completely stop this decline, we can slow it down with pure NMN powder. NMN powder—Nicotinamide Mononucleotide—is a derivative of Vitamin B3 (Niacin). It is a potent anti-aging molecule that helps counter the effects of growing age. Moreover, it increases overall body energy, reducing tiredness. In simpler words, NMN is a total game changer in age vs. health combat! So, what is NMN powder, and how can you use it to maximize your health? Read on to find out all. What is Beta-Nicotinamide Mononucleotide (NMN)? NMN, or Beta-Nicotinamide Mononucleotide, is a precursor molecule of NAD+ (Nicotinamide Adenine Dinucleotide) in the body. Research has shown that NAD+ combines with particular molecules called sirtuins to enhance longevity, which is achieved by converting food molecules into energy packets that are later used to carry out bodily functions[1]. NAD+ is also a crucial component of the body's age cycle. It regulates cellular health by acting on anti-aging genes and turning them on and off to regulate metabolism. However, NAD+ only has limited body stores. Therefore, a decrease in NAD+ leads to aging. Pure NMN powder prevents this decline by complementing the NAD+ deficiency, ultimately leading to a better life expectancy. Potential Benefits of Pure NMN Powder David Sinclair, a Harvard professor of genetics, has been working on the benefits of pure NMN powder for aging for decades. According to David Sinclair's NMN research and existing studies, the role of NMN is that of an activator. Based on this role, NMN provides the following benefits to the body: 1. May Boost NAD+ Levels in the Body Acting as a moderator, NMN converts NAD into activated forms. It helps increase energy production in the body, making you feel energized. The activated NAD+ then performs vital functions of the body, like: * Reduced inflammation * Stress resistance * Maintaining circadian rhythms * DNA repairs * Boosting energy metabolism * Improving athletic performance 2. May Improve Metabolic Health and General Wellness Pure NMN powder raises NAD+ levels throughout your body. With a healthy diet and lifestyle, it may be helpful for old-age problems and chronic diseases, improving overall health. These might include: * Protect the cardiovascular and cerebrovascular * Prevent cancer * Regulates blood sugar * Help with weight loss * Improve sleeping * Prevent neurodegenerative diseases * Auxiliary hypolipidemic * Auxiliary hypoglycemic * Hearing and vision protectionPromote alcohol metabolism, hangover and protect the liver 3. May Offer Anti-Aging Effects NAD+ is a key player in our body's energy production and DNA repair processes. Pure NMN powder holds promise as a potential anti-aging agent by bolstering intracellular NAD+ levels. NMN may exert further anti-aging effects by enhancing mitochondrial function and potentially lengthening telomeres. Though the precise mechanisms underlying NMN's anti-aging properties are still under investigation, its potential to support cellular health and longevity by utilizing pure NMN powders effectively. Top 4 Applications of Pure NMN Powder Pure NMN can stand as a versatile supplement and is easily incorporated into our daily lives. Common dosage forms of NMN products may include capsules, tablets, granules, powder, candies, and beverages. With its potential benefits, pure NMN powder finds utility across multiple fields: 1. Health Care Products NMN supplements are used to treat a variety of health conditions. It is touted for its anti-aging properties and potential benefits for metabolism and overall health. Whether it's being used in an anti-aging supplement or a sleep aid, pure NMN powder holds promise for potentially slowing the effects of aging or enhancing sleep quality. 2. Cosmetic Raw Materials NMN also improves skin metabolism by boosting NAD+ production. It further helps to fight off skin problems, increases new regeneration, and creates a glow from within. It is widely used in some anti-aging skincare formulations and for moisturizing and repairing cosmetic products. 3. Functional Food Additives Pure NMN powder is also a functional food additive. It enhances mental concentration and physical vigor, particularly in situations demanding sustained energy. It is frequently found in energy drinks and various health foods like energy bars, gummies, and cereals. 4. Animal Health Last but not least, animal health also benefits from NMN powder. When used in medical treatments and animal feeds, they help boost overall physiological functions and promote vitality. It helps increase the overall life span of animals. BONTAC's Premium Quality Wholesale Pure NMN Powder The efficacy of NMN depends on the quality and purity of the product. Thus, always use high-quality and original NMN products for ideal results. BONTAC is a well-known brand among bio-engineered NMN suppliers. We are the raw material supplier for the NMN study of David Sinclair's team. At the same time, we are also the sole provider of raw materials for clinical trials in many well-known institutions in Japan and the United States. We are known for our premium-quality, pure NMN powder. Our NMN powder is white with no visible impurities. It has a unique smell and a balanced pH (3.0-4.0), offering up to 99.5% purity. Our product advantages include: * 21 domestic and international NMN patents and multiple international certifications * Exclusive “Bonpure” seven-step purification technology, high purity (up to 99.9%) and stability * “Bonzyme” whole-enzymatic method, no harmful solvent residues, environmental-friendly * Multiple in vivo studies show that BONTAC NMN is safe and effective * One-stop customized product solution * Self-owned factories, high quality and stable supply of products All these leading industrial technologies and advantages make BONTAC the best NMN supplier in the biotech industry. IFrame Source: https://www.youtube.com/watch?v=FYkkJfuwttg Final Thoughts NMN has great potential for skin, heart, gut, and aging concerns. When you choose BONTAC, expect nothing but pure NMN powder of unparalleled purity and quality. BONTAC also offers wholesale purchases of NMN powder bulk and a one-stop solution for large businesses. Contact us and get the latest information on product availability. References [1] Why Is Longevity Still a Scientific Mystery? Sirtuins—Past, Present and Future. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9821238/ (Accessed: 6 May 2024)

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